Product introduction
Glimison-M 1 Tablet PR is a two-in-one prolonged-release antidiabetic tablet combining glimepiride 1mg and metformin 500mg. It is prescribed for adults with type 2 diabetes who need more than one medicine to keep blood sugar in range. The prolonged-release design releases metformin gradually through the day.
Storage: Store below 30°C, away from moisture and direct sunlight, and keep out of reach of children.
Uses of Glimison-M 1 Tablet PR
- Type 2 diabetes mellitus in adults.
Benefits of Glimison-M 1 Tablet PR
By pairing two drugs that act in different ways, this tablet controls blood glucose more effectively than either alone for many people. It simplifies the regimen to fewer tablets, which can make it easier to stay consistent. Better sugar control over time reduces the risk of long-term diabetic complications.
Side effects of Glimison-M 1 Tablet PR
Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.
- Nausea.
- Vomiting.
- Diarrhea.
- Abdominal pain.
- Loss of appetite.
- Low blood sugar (hypoglycemia).
- Altered taste.
- Headache.
- Upper respiratory tract infection.
- Weight gain.
How to use Glimison-M 1 Tablet PR
Swallow the tablet with water during or just after a meal, at about the same time each day, exactly as your doctor has directed. Taking it with food reduces stomach upset. Do not change the dose by yourself.
How Glimison-M 1 Tablet PR works
Glimepiride prompts the pancreas to release more insulin. Metformin reduces the amount of glucose the liver produces, slows glucose absorption from the gut and helps the body respond better to insulin. Together they lower blood sugar through complementary routes.
Substitutes for Glimison-M 1 Tablet PR
These medicines have the same composition (Glimepiride (1mg) + Metformin (500mg)) and can generally be used as alternatives. Always confirm with your doctor or our pharmacist before switching.
Safety advice
Alcohol increases the risk of low blood sugar and lactic acidosis. It is best avoided completely while on this medicine.
Animal studies have shown risk to the foetus. Your doctor will usually recommend an alternative such as insulin during pregnancy.
The components may pass into breast milk. Use only if your doctor judges the benefit to outweigh the risk.
Very low or very high blood sugar can impair alertness. Do not drive if your sugar is off target or you feel unwell.
Metformin builds up in kidney disease and raises the risk of lactic acidosis, so this combination is generally avoided. Your doctor will decide.
It is generally avoided in liver disease. Your doctor will advise whether it is suitable for you.
Quick tips
- Take it with meals at the same time every day to lessen stomach upset and keep levels steady.
- Learn the signs of low blood sugar, such as sweating, shakiness and dizziness, and keep a sugary snack handy.
- Avoid alcohol, since it raises the risk of both low blood sugar and a rare but serious condition called lactic acidosis.
- Tell your doctor if you notice rapid breathing, unusual tiredness or persistent stomach pain, and inform them before any surgery or contrast scan.
- Monitor your blood sugar regularly and combine the medicine with a healthy diet and exercise.
Fact box
| Chemical class | Sulfonylurea and biguanide combination |
|---|---|
| Habit forming | No |
| Therapeutic class | Anti Diabetic |
| Action class | Oral antidiabetics |
Frequently asked questions
What does the PR in Glimison-M 1 Tablet PR mean?
PR stands for prolonged release. The tablet is built to release its medicine slowly over several hours, so it should be swallowed whole and never crushed or chewed.
Should I take it before or after food?
Take it with or just after a meal. This helps your stomach tolerate the metformin and lowers the chance of low sugar from glimepiride.
Can I miss a dose if I skip a meal?
If you are skipping a meal, ask your doctor how to handle the dose. Taking it without food can cause blood sugar to fall too low.
Is long-term use of this tablet safe?
It is meant for long-term use under medical supervision. Your doctor may check kidney function, liver function and vitamin B12 levels periodically.