Glimestar M1 Tablet PR

Glimepiride (1mg) + Metformin (500mg)

Marketed by Mankind Pharma Ltd

Prescription requiredStrip of 15 Tablets PR
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Product introduction

Glimestar M1 Tablet PR is a prolonged-release combination medicine used to manage type 2 diabetes. It brings together glimepiride, which nudges the pancreas to release more insulin, and metformin, which cuts down excess glucose production in the liver. Made by Mankind Pharma Ltd, the prolonged-release format is designed to release the medicine gradually so blood sugar stays steadier through the day. It is meant to work alongside a diabetes-friendly diet and regular physical activity, not replace them.

Storage: Store below 30°C in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.

Uses of Glimestar M1 Tablet PR

  • Control of high blood sugar in type 2 diabetes
  • Used when diet and exercise alone cannot manage glucose levels
  • May be prescribed alongside other diabetes medicines as advised by a doctor

Benefits of Glimestar M1 Tablet PR

Helps bring fasting and post-meal blood sugar closer to target levels,Prolonged-release format supports steadier glucose control with once-daily dosing,Dual mechanism tackles diabetes from two directions — more insulin release plus less liver glucose output

Side effects of Glimestar M1 Tablet PR

Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.

  • Nausea
  • Diarrhea
  • Abdominal pain
  • Loss of appetite
  • Vomiting

How to use Glimestar M1 Tablet PR

Take with or after a meal, generally at the same time each day,Swallow the tablet whole with water; do not crush or chew a prolonged-release tablet,Do not skip the meal that follows the dose, since this can affect blood sugar control

How Glimestar M1 Tablet PR works

Glimepiride stimulates the pancreas to release more insulin, which helps cells absorb glucose from the blood,Metformin reduces the amount of glucose the liver produces and improves how well the body responds to its own insulin,Together, the two actions lower blood glucose more effectively than either medicine alone, while the prolonged-release form spreads the effect over the day

Substitutes for Glimestar M1 Tablet PR

These medicines have the same composition (Glimepiride (1mg) + Metformin (500mg)) and can generally be used as alternatives. Always confirm with your doctor or our pharmacist before switching.

Safety advice

AlcoholUNSAFE

Drinking alcohol with this medicine can increase the risk of low blood sugar and should be avoided.

PregnancyUNSAFE

Not recommended during pregnancy; consult your doctor about safer alternatives for blood sugar control.

BreastfeedingUNSAFE

May not be safe while breastfeeding; discuss suitable options with your doctor.

DrivingCAUTION

May affect alertness if blood sugar drops too low or rises too high, so drive only if you feel well.

KidneyUNSAFE

Not recommended for patients with kidney disease; dose adjustment or an alternative may be needed.

LiverUNSAFE

Not recommended for patients with liver disease; talk to your doctor before use.

Quick tips

  • Take the tablet at the same time every day to build a routine
  • Never skip a meal after taking this medicine, as it can trigger low blood sugar
  • Check blood sugar levels regularly as advised by your doctor
  • Keep a fast-acting sugar source handy in case of hypoglycemia symptoms like shakiness or sweating
  • Avoid alcohol, as it can increase the risk of low blood sugar

Fact box

Chemical classSulfonylurea + Biguanide combination
Habit formingNo
Therapeutic classAnti Diabetic
Action classNot specified

Frequently asked questions

What is Glimestar M1 Tablet PR used for?

It is used to help control blood sugar levels in adults with type 2 diabetes, usually alongside a healthy diet and regular exercise.

Can I stop taking it once my sugar levels are normal?

No, stopping suddenly without medical advice can cause blood sugar to rise again. Always consult your doctor before changing the dose or stopping.

Does this medicine cause low blood sugar?

Yes, it can, especially if a meal is skipped or delayed. Watch for symptoms like sweating, shakiness, or dizziness and keep a sugar source nearby.

Should I take it before or after food?

It is generally taken with or right after a meal to reduce stomach upset and support steady blood sugar control.

Is this tablet safe for someone with kidney problems?

It is generally not recommended for people with kidney disease. Your doctor will assess whether it is suitable or suggest an alternative.

Disclaimer: This information is for general awareness only and is not a substitute for professional medical advice. Always consult a doctor or our pharmacist before starting, stopping or changing any medicine. Medicines are dispensed only against a valid prescription where required.
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