Product introduction
Apriglim-M1 Tablet PR is a combination medicine used to manage type 2 diabetes in adults. It brings together two well-established anti-diabetic drugs, glimepiride and metformin, in a single prolonged-release tablet. It is usually prescribed when blood sugar is not adequately controlled by one medicine alone, or for people already stabilised on the two ingredients taken separately. Alongside a healthy diet and regular exercise, it helps keep blood glucose within a target range.
Storage: Store below 30°C.
Uses of Apriglim-M1 Tablet PR
- Treatment of type 2 diabetes mellitus
Benefits of Apriglim-M1 Tablet PR
Apriglim-M1 helps bring high blood sugar under control by working in two complementary ways: it prompts the pancreas to release more insulin and it reduces the amount of glucose made by the liver. Keeping blood sugar well managed over time lowers the risk of the serious long-term complications of diabetes, such as kidney damage, eye problems, nerve damage and problems that can lead to limb loss. For the medicine to work well, it should be combined with a balanced diet, regular physical activity and any other measures your doctor recommends.
Side effects of Apriglim-M1 Tablet PR
Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.
- Headache
- Low blood sugar (hypoglycemia)
- Nausea
- Diarrhea
- Abdominal pain
- Loss of appetite
- Vomiting
- Altered taste
- Upper respiratory tract infection
- Weight gain
How to use Apriglim-M1 Tablet PR
Take this tablet in the dose and for the duration advised by your doctor. Swallow it whole with water, ideally with or just after food to reduce the chance of an upset stomach. Take it at around the same time each day.
How Apriglim-M1 Tablet PR works
Apriglim-M1 pairs two anti-diabetic medicines. Glimepiride belongs to the sulfonylurea group and works by stimulating the pancreas to release more insulin, which helps lower blood glucose. Metformin belongs to the biguanide group and works mainly by reducing the amount of glucose the liver produces and by improving the body's response to insulin. Together they help control blood sugar more effectively than either would alone.
Substitutes for Apriglim-M1 Tablet PR
These medicines have the same composition (Glimepiride (1mg) + Metformin (500mg)) and can generally be used as alternatives. Always confirm with your doctor or our pharmacist before switching.
Safety advice
It is unsafe to drink alcohol with this medicine, as it can affect your blood sugar. Please avoid alcohol.
This medicine is not recommended in pregnancy, as there is evidence of possible risk to the baby. Consult your doctor.
This medicine may be unsafe during breastfeeding. Please talk to your doctor before using it.
Your ability to drive may be affected if your blood sugar becomes too low or too high. Be cautious.
This medicine is not considered safe for people with kidney disease and is best avoided. Consult your doctor.
This medicine is not considered safe for people with liver disease and is best avoided. Consult your doctor.
Quick tips
- Keep up regular exercise, a healthy diet and any other diabetes medicines exactly as prescribed.
- Take the tablet with food to lessen the chance of stomach upset.
- Check your blood sugar regularly as advised by your doctor.
- Carry a fast-acting sugar source such as glucose sweets or juice in case your blood sugar drops too low.
- Avoid alcohol, and tell your doctor at once about deep or rapid breathing, ongoing nausea, vomiting or stomach pain.
- Your doctor may check your liver and kidney function from time to time.
Fact box
| Chemical class | Sulfonylurea + Biguanide combination |
|---|---|
| Habit forming | No |
| Therapeutic class | ANTI DIABETIC |
| Action class | — |
Frequently asked questions
What is Apriglim-M1 Tablet PR used for?
It is used to manage type 2 diabetes in adults, usually when a single anti-diabetic medicine is not enough to keep blood sugar controlled.
Why should I take it with food?
Taking the tablet with or just after a meal helps reduce stomach-related side effects such as nausea and abdominal discomfort.
Can this medicine cause low blood sugar?
Yes. Because it increases insulin release, it can lower blood sugar too much. Carry a quick sugar source and learn the warning signs, such as sweating, shakiness and dizziness.
Should I avoid alcohol while taking it?
Yes. Alcohol can upset your blood sugar control and is unsafe with this medicine, so it is best avoided.
Can I stop taking it once my sugar is normal?
No. Do not stop without your doctor's advice, even if you feel well. Diabetes usually needs ongoing treatment to stay controlled.