Product introduction
Sitason-M 50/500 combines sitagliptin with metformin in one tablet to help control blood sugar in type 2 diabetes when a single medicine is not enough. It is a prescription-only medicine.
Storage: Store below 30°C, away from moisture and direct light.
Uses of Sitason-M 50/500 Tablet
- Type 2 diabetes mellitus.
Benefits of Sitason-M 50/500 Tablet
Two medicines that work in different ways give better glucose control than either alone, helping lower the risk of long-term complications affecting the kidneys, eyes, heart and brain.
Side effects of Sitason-M 50/500 Tablet
Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.
- Diarrhoea.
- Stomach pain.
- Flatulence.
- Constipation.
- Vomiting.
- Nausea.
- Rarely lactic acidosis or vitamin B12 deficiency.
How to use Sitason-M 50/500 Tablet
Swallow the tablet whole with or after a meal. Do not chew or crush it. Take it exactly as your doctor has prescribed.
How Sitason-M 50/500 Tablet works
Sitagliptin increases insulin release and reduces the glucose made by the liver, while metformin lowers liver glucose output and helps the body respond better to insulin.
Substitutes for Sitason-M 50/500 Tablet
These medicines have the same composition (Sitagliptin (50mg) + Metformin (500mg)) and can generally be used as alternatives. Always confirm with your doctor or our pharmacist before switching.
Safety advice
Avoid alcohol; it can upset blood sugar and raise the risk of lactic acidosis with metformin.
Considered unsafe in pregnancy; your doctor will usually switch to a safer option.
Not recommended while breastfeeding.
Effect on concentration is unclear; avoid driving if you feel unwell.
Dose adjustment may be needed, and it may need to be avoided in significant kidney impairment.
Not recommended in patients with liver disease.
Quick tips
- Take it with meals to reduce stomach upset.
- Keep following your diet and exercise plan.
- Check your blood sugar regularly as advised.
- Avoid alcohol while on this medicine.
- Seek urgent medical help for unusual tiredness, rapid breathing or stomach pain.
Fact box
| Chemical class | — |
|---|---|
| Habit forming | No |
| Therapeutic class | ANTI-DIABETIC |
| Action class | Oral antidiabetics |
Frequently asked questions
What is Sitason-M used for?
It is used to control blood sugar in adults with type 2 diabetes.
Why take it with food?
Taking it with meals reduces the stomach upset that metformin can cause.
What is lactic acidosis?
It is a rare but serious build-up of lactic acid; seek urgent medical help if you notice unusual tiredness, fast breathing or stomach pain.
Can metformin affect vitamin B12?
Long-term use can lower vitamin B12, so your doctor may check your levels.