Istamet 50mg/500mg Tablet

Sitagliptin (50mg) + Metformin (500mg)

Marketed by Sun Pharmaceutical Industries Ltd

Prescription required15 tablets in 1 strip
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Product introduction

Istamet 50mg/500mg Tablet contains sitagliptin and metformin and is prescribed for type 2 diabetes. Doctors often choose it when metformin alone is not controlling blood sugar enough. It is dispensed on prescription.

Storage: Keep below 30°C.

Uses of Istamet 50mg/500mg Tablet

  • Type 2 diabetes mellitus.

Benefits of Istamet 50mg/500mg Tablet

Using two complementary medicines can improve blood sugar control more than one alone. A single combined tablet is easier to take regularly. Better control over time helps lower the risk of diabetes-related complications.

Side effects of Istamet 50mg/500mg Tablet

Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.

  • Diarrhoea.
  • Stomach pain.
  • Flatulence.
  • Constipation.
  • Vomiting.
  • Nausea.

How to use Istamet 50mg/500mg Tablet

Take the tablet with water along with food, in the dose and timing your doctor has prescribed. Do not stop or change the dose on your own, and continue with your diet and exercise plan.

How Istamet 50mg/500mg Tablet works

Sitagliptin helps the pancreas make more insulin, supports effective insulin use and lowers the sugar released by the liver. Metformin reduces liver glucose production, slows glucose absorption from the gut and makes the body more sensitive to insulin.

Substitutes for Istamet 50mg/500mg Tablet

These medicines have the same composition (Sitagliptin (50mg) + Metformin (500mg)) and can generally be used as alternatives. Always confirm with your doctor or our pharmacist before switching.

Safety advice

AlcoholUNSAFE

It is unsafe to consume alcohol with this medicine.

PregnancyUNSAFE

It carries a risk of harm to the unborn baby, so it is considered unsafe in pregnancy.

BreastfeedingUNSAFE

It may be harmful to the nursing infant and is not considered safe while breastfeeding.

DrivingCONSULT YOUR DOCTOR

Its effect on concentration is not known. Ask your doctor before driving.

KidneyCAUTION

The dose needs adjustment in severe kidney disease, so use only under medical supervision.

LiverUNSAFE

It should be avoided in liver disease.

Quick tips

  • Take it with food to reduce stomach upset.
  • Avoid alcohol while on this medicine.
  • Keep regular appointments for blood sugar and kidney tests.
  • Do not stop taking it just because sugar levels look normal.
  • Contact your doctor if you have persistent vomiting or severe stomach pain.

Fact box

Chemical classDPP-4 inhibitor + Biguanide
Habit formingNo
Therapeutic classANTI DIABETIC
Action classOral Antidiabetics

Frequently asked questions

What is Istamet 50mg/500mg used for?

It is used to control blood sugar in people with type 2 diabetes.

When is it usually prescribed?

It is often prescribed when metformin alone does not give enough control.

Can I drink alcohol while taking it?

No, alcohol is unsafe with this medicine.

Does it need a prescription?

Yes, it is a prescription-only medicine.

Disclaimer: This information is for general awareness only and is not a substitute for professional medical advice. Always consult a doctor or our pharmacist before starting, stopping or changing any medicine. Medicines are dispensed only against a valid prescription where required.
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