Product introduction
Glimison-M 2 Tablet PR is a prolonged-release combination tablet containing glimepiride 2mg and metformin 500mg. It is prescribed to adults with type 2 diabetes when lifestyle measures alone are not enough to control blood sugar. It is the higher glimepiride strength of the Glimison-M range.
Storage: Store below 30°C, away from moisture and direct sunlight, and keep out of reach of children.
Uses of Glimison-M 2 Tablet PR
- Type 2 diabetes mellitus in adults.
- Blood sugar control when diet, exercise and weight reduction alone are not enough.
Benefits of Glimison-M 2 Tablet PR
Two medicines in one tablet give a stronger and more convenient sugar-lowering effect than a single drug for many patients. Fewer tablets can help you stick to the treatment plan. Steady glucose control lowers the chance of complications affecting the eyes, kidneys, nerves and heart.
Side effects of Glimison-M 2 Tablet PR
Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.
- Nausea.
- Vomiting.
- Diarrhea.
- Abdominal pain.
- Loss of appetite.
- Low blood sugar (hypoglycemia).
- Taste changes.
- Headache.
- Upper respiratory tract infection.
How to use Glimison-M 2 Tablet PR
Swallow the tablet whole with water, with or just after food, at the same time each day. Your doctor decides the dose according to your blood sugar response, so do not alter it yourself.
How Glimison-M 2 Tablet PR works
Glimepiride increases insulin release from the pancreas. Metformin lowers glucose production by the liver, delays glucose absorption in the intestine and improves how the body responds to insulin. The combination tackles high blood sugar from several angles.
Substitutes for Glimison-M 2 Tablet PR
These medicines have the same composition (Glimepiride (2mg) + Metformin (500mg)) and can generally be used as alternatives. Always confirm with your doctor or our pharmacist before switching.
Safety advice
Drinking alcohol with this medicine raises the risk of dangerously low sugar and lactic acidosis. Avoid it.
It is generally not recommended, as animal studies have shown risk to the foetus. Your doctor will suggest a safer alternative if needed.
The medicine may pass into breast milk. It should be used only if your doctor feels the benefit outweighs the risk.
Do not drive if your blood sugar is too low or too high, or if you feel dizzy or unwell.
It is not suitable in kidney disease because metformin can accumulate. Regular monitoring is essential if your doctor still prescribes it.
It should not be used in severe liver disease. Follow your doctor's guidance.
Quick tips
- Take it with or after meals every day at a consistent time.
- Know the early signs of low blood sugar, including sweating, dizziness, headache and shaking, and carry a fast-acting sugar source.
- Keep exercising and eating a balanced diet, as the tablet works best alongside these habits.
- Seek medical help promptly if you develop deep or rapid breathing or ongoing nausea, as these can signal lactic acidosis.
- Tell your doctor before any surgery under general anaesthesia, and expect periodic liver function checks.
Fact box
| Chemical class | Sulfonylurea and biguanide combination |
|---|---|
| Habit forming | No |
| Therapeutic class | Anti Diabetic |
| Action class | Oral antidiabetics |
Frequently asked questions
How is Glimison-M 2 different from Glimison-M 1?
Both contain 500mg of metformin, but Glimison-M 2 has 2mg of glimepiride whereas Glimison-M 1 has 1mg. Your doctor selects the strength based on your blood sugar needs.
Can I crush the tablet if it is hard to swallow?
No. It is a prolonged-release tablet and must be swallowed whole. Ask your doctor about alternatives if swallowing is difficult.
What if I forget a dose?
Take it as soon as you remember with food. If it is almost time for the next dose, skip the missed one and never double up.
Will this medicine cause low blood sugar?
It can, particularly if you skip meals, exercise heavily or drink alcohol. Recognise the symptoms early and keep a sugary snack at hand.