Glimestar M2 Tablet PR

Glimepiride (2mg) + Metformin (500mg)

Marketed by Mankind Pharma Ltd

Prescription requiredStrip of 15 Tablets PR
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Product introduction

Glimestar M2 Tablet PR is a prolonged-release combination of glimepiride 2mg and metformin 500mg, used to manage type 2 diabetes. It is a stronger version of the 1mg formulation, intended for patients whose blood sugar needs more support than the lower dose provides. Manufactured by Mankind Pharma Ltd, the prolonged-release design allows the medicine to act steadily over the day. It should always be used alongside the diet and lifestyle changes recommended by a doctor.

Storage: Store below 30°C in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.

Uses of Glimestar M2 Tablet PR

  • Control of high blood sugar in type 2 diabetes
  • Used when diet and exercise alone are not enough to manage glucose levels
  • Suitable for patients who need a higher glimepiride dose than the 1mg strength

Benefits of Glimestar M2 Tablet PR

Provides stronger glucose-lowering support for patients needing a higher glimepiride dose,Prolonged-release format allows once-daily dosing with a steady effect,Combines two complementary mechanisms for more consistent blood sugar control

Side effects of Glimestar M2 Tablet PR

Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.

  • Nausea
  • Diarrhea
  • Abdominal pain
  • Loss of appetite
  • Vomiting

How to use Glimestar M2 Tablet PR

Take with or after a meal, ideally at the same time each day,Swallow the tablet whole with water; do not crush, break, or chew it,Do not skip the meal that follows the dose, as this raises the risk of low blood sugar

How Glimestar M2 Tablet PR works

Glimepiride prompts the pancreas to release more insulin, helping the body move glucose out of the bloodstream,Metformin reduces glucose production in the liver and improves the body's sensitivity to insulin,The combined, prolonged-release action helps keep blood sugar levels steadier across the day compared to either ingredient alone

Substitutes for Glimestar M2 Tablet PR

These medicines have the same composition (Glimepiride (2mg) + Metformin (500mg)) and can generally be used as alternatives. Always confirm with your doctor or our pharmacist before switching.

Safety advice

AlcoholUNSAFE

Drinking alcohol with this medicine raises the risk of low blood sugar and should be avoided.

PregnancyUNSAFE

Not recommended during pregnancy due to possible risk to the baby; discuss alternatives with your doctor.

BreastfeedingUNSAFE

May not be safe while breastfeeding; ask your doctor about safer options.

DrivingCAUTION

May affect alertness if blood sugar drops too low or rises too high, so drive only if you feel well.

KidneyUNSAFE

Not recommended for patients with kidney disease; an alternative or dose change may be needed.

LiverUNSAFE

Not recommended for patients with liver disease; consult your doctor before use.

Quick tips

  • Take the tablet at a fixed time daily to maintain steady blood sugar control
  • Never skip meals after dosing, since this can trigger hypoglycemia
  • Get blood sugar levels checked regularly as your doctor recommends
  • Carry a fast-acting sugar source in case of low blood sugar symptoms
  • Limit or avoid alcohol, which can increase the risk of low blood sugar

Fact box

Chemical classSulfonylurea + Biguanide combination
Habit formingNo
Therapeutic classAnti Diabetic
Action classNot specified

Frequently asked questions

What is Glimestar M2 Tablet PR used for?

It helps control blood sugar in adults with type 2 diabetes, generally when a lower-dose combination hasn't been enough on its own.

How is this different from Glimestar M1?

It contains a higher dose of glimepiride (2mg instead of 1mg), combined with the same 500mg of metformin, for patients who need stronger glucose control.

Can this tablet cause hypoglycemia?

Yes, especially if meals are skipped or delayed. Watch for sweating, shakiness, or dizziness and treat promptly with a sugar source.

Is it safe to drink alcohol on this medicine?

No, alcohol can increase the risk of low blood sugar and is best avoided while taking this tablet.

Do I need a prescription to buy this?

Yes, this is a prescription-only medicine and should be taken exactly as your doctor directs.

Disclaimer: This information is for general awareness only and is not a substitute for professional medical advice. Always consult a doctor or our pharmacist before starting, stopping or changing any medicine. Medicines are dispensed only against a valid prescription where required.
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