Product introduction
Zoryl M 3 Tablet PR is a prolonged-release combination tablet used to manage type 2 diabetes mellitus. It combines glimepiride 3mg, a sulfonylurea that boosts the pancreas's own insulin output, with metformin 500mg, a biguanide that reduces glucose production in the liver and improves insulin sensitivity. The 3mg strength of glimepiride is generally used in patients whose blood sugar has not responded adequately to lower doses. As with other prolonged-release formulations, it is designed to release the medicine steadily so a single daily dose can help control blood glucose through the day.
Storage: Store below 25°C, in a cool, dry place away from direct sunlight and moisture.
Uses of Zoryl M 3 Tablet PR
- Long-term management of type 2 diabetes mellitus
- Used when a lower dose of glimepiride has not achieved adequate blood sugar control
- Used alongside diet and exercise to control blood glucose levels
- Helps reduce the risk of diabetes-related complications
Benefits of Zoryl M 3 Tablet PR
Combines two proven anti-diabetic actions in one tablet, which can simplify a treatment routine that would otherwise need separate medicines,A higher glimepiride strength may suit patients who need more pronounced insulin stimulation to reach their target blood sugar,Consistent blood sugar control over time may reduce the likelihood of complications affecting the eyes, kidneys, nerves and blood vessels
Side effects of Zoryl M 3 Tablet PR
Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.
- Nausea
- Diarrhoea
- Abdominal pain
- Loss of appetite
- Low blood sugar (hypoglycaemia)
- Altered taste
How to use Zoryl M 3 Tablet PR
Take the tablet with or immediately after a meal, as advised by your doctor,Swallow it whole with water; do not chew or crush the prolonged-release tablet,Take it at a fixed time each day to maintain steady drug levels in the body
How Zoryl M 3 Tablet PR works
Glimepiride stimulates the pancreas to release additional insulin into the bloodstream,Metformin lowers the amount of sugar released by the liver and helps body tissues use insulin more effectively,The combined effect brings blood glucose down through two separate pathways, which can be more effective than either component alone
Substitutes for Zoryl M 3 Tablet PR
No other medicine with the same composition is listed in our catalogue yet. Message us on WhatsApp and our pharmacist will help you find a suitable alternative.
Safety advice
Alcohol can heighten the blood-sugar-lowering effect of this medicine and raises the risk of hypoglycaemia, so it should be avoided.
This medicine is not usually recommended in pregnancy; your doctor will weigh the risks and benefits before prescribing it.
As the medicine may pass into breast milk, a doctor should be consulted before use during breastfeeding.
Fluctuations in blood sugar caused by this medicine may impair alertness, so take care while driving or operating machinery.
This medicine is not advised for people with significant kidney disease, especially at higher doses.
It is not recommended for people with liver disease, as impaired liver function can affect how the medicine is processed.
Quick tips
- Do not delay or skip meals after taking this tablet to avoid a sudden drop in blood sugar
- Carry a quick source of sugar, like glucose tablets or a sweet, in case of hypoglycaemia symptoms
- Have your blood sugar, HbA1c and kidney function monitored regularly as your doctor recommends
- Limit or avoid alcohol, since it raises the chance of low blood sugar episodes
- Continue taking this medicine regularly even if you feel fine, unless your doctor advises otherwise
Fact box
| Chemical class | Sulfonylurea + Biguanide |
|---|---|
| Habit forming | No |
| Therapeutic class | Anti Diabetic |
| Action class | Oral Antidiabetics |
Frequently asked questions
Why is the glimepiride dose higher in this tablet compared to Zoryl M 1?
The 3mg strength is prescribed when a lower dose of glimepiride has not achieved adequate blood sugar control.
Can I switch from Zoryl M 1 to Zoryl M 3 on my own?
No, any change in dose or strength should only be made by your doctor based on your blood sugar readings.
What happens if I take an extra tablet by mistake?
An accidental extra dose can cause severe low blood sugar; contact your doctor or seek medical help immediately.
Does this medicine cure diabetes?
No, it helps control blood sugar levels but does not cure diabetes; it needs to be taken continuously as prescribed.
Can this tablet be taken by elderly patients?
It can be used in elderly patients but often at a more cautious dose, since they may be more prone to low blood sugar.