Product introduction
Vymada 50 Tablet is the starting-dose version of a combination medicine used to treat chronic heart failure. It pairs sacubitril and valsartan, two active ingredients that work together to reduce strain on a weakened heart muscle. Doctors often begin treatment with this lower strength before gradually increasing the dose based on how well a patient tolerates it. Like its higher-strength counterpart, it belongs to the ARNI class of heart failure medicines.
Storage: Store below 30°C in a cool, dry place away from direct sunlight and moisture.
Uses of Vymada 50 Tablet
- Chronic heart failure with reduced ejection fraction
- To reduce the risk of hospitalization from worsening heart failure
- As a starting-dose option when beginning ARNI therapy
- To lower the risk of cardiovascular death in heart failure patients
Benefits of Vymada 50 Tablet
Eases the workload on a weakened heart by relaxing blood vessels,May lower the chances of being hospitalized for worsening heart failure,Provides a gentler starting dose for patients newly beginning ARNI therapy
Side effects of Vymada 50 Tablet
Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.
- Low blood pressure (dizziness or lightheadedness)
- Elevated potassium levels in the blood
- Dry, persistent cough
- Reduced kidney function
- Fatigue
- Nausea
How to use Vymada 50 Tablet
Take Vymada 50 Tablet as directed by your doctor, generally twice daily, with or without food.,Swallow it whole with water; avoid crushing or chewing it unless instructed otherwise.,Your doctor may increase the dose after a few weeks depending on how well your body tolerates it.
How Vymada 50 Tablet works
Vymada 50 Tablet combines sacubitril, which slows the breakdown of natural hormones that widen blood vessels and help the body clear excess salt and water, with valsartan, which blocks a hormone that would otherwise tighten blood vessels and raise blood pressure.,This combined action reduces the pressure the heart has to pump against, making it easier for a weakened heart to circulate blood.,Starting at this lower strength lets the body adjust to the ARNI combination before the dose is stepped up if needed.
Substitutes for Vymada 50 Tablet
No other medicine with the same composition is listed in our catalogue yet. Message us on WhatsApp and our pharmacist will help you find a suitable alternative.
Safety advice
There isn't enough information on how alcohol interacts with Vymada 50 Tablet, so ask your doctor before drinking.
This medicine can harm a developing baby and should not be used during pregnancy; your doctor will typically recommend a safer alternative if you are pregnant or planning to be.
Limited evidence suggests this medicine may pass into breast milk, so it is generally considered unsafe during breastfeeding; discuss alternatives with your doctor.
It isn't well established whether this medicine affects driving ability, but avoid driving if you feel dizzy or lightheaded after a dose.
Patients with severe kidney disease may need a dose adjustment and closer monitoring while taking this medicine.
Use with caution in mild-to-moderate liver disease; it is generally avoided in patients with severe liver impairment.
Quick tips
- Do not stop taking this medicine on your own, even once symptoms improve.
- Have your blood pressure, potassium, and kidney function tested periodically as your doctor recommends.
- Do not take this together with an ACE inhibitor; a washout gap is required when switching between the two.
- Rise slowly from sitting or lying positions to reduce the chance of feeling dizzy.
- Attend follow-up visits so your doctor can decide if a dose increase is appropriate for you.
Fact box
| Chemical class | Angiotensin Receptor Neprilysin Inhibitor (ARNI) |
|---|---|
| Habit forming | No |
| Therapeutic class | Cardiac |
| Action class | Angiotensin Receptor Neprilysin Inhibitors (ARNI) |
Frequently asked questions
Why would my doctor start me on Vymada 50 Tablet instead of a higher strength?
Doctors often begin ARNI therapy at this lower dose to see how the body responds before gradually increasing the strength, which helps reduce the chance of side effects like low blood pressure.
Can I switch from an ACE inhibitor directly to Vymada 50 Tablet?
No, a gap of at least 36 hours is usually required after stopping an ACE inhibitor before starting this medicine, to lower the risk of a serious reaction called angioedema; follow your doctor's specific instructions.
What should I do if I miss a dose of Vymada 50 Tablet?
Take it as soon as you remember, but if your next dose is almost due, skip the missed one rather than taking two doses together.
Will I eventually be moved to Vymada 100 Tablet?
Possibly — if you tolerate Vymada 50 Tablet well, your doctor may increase the strength over time to get the best long-term benefit for your heart failure.
Does Vymada 50 Tablet cure heart failure?
No, it manages the condition rather than curing it, so it needs to be taken continuously alongside other prescribed heart failure treatments and lifestyle changes.