Product introduction
Pregason-NT is a combination tablet of pregabalin and nortriptyline, two medicines that act on the nervous system in different ways. It is prescribed for persistent nerve pain, the type caused by damaged or irritated nerves rather than by tissue injury. It must be used under medical supervision.
Storage: Store below 25°C, protected from light and moisture.
Uses of Pregason-NT 75mg/10mg Tablet
- Neuropathic (nerve) pain.
- Nerve pain from diabetes.
- Nerve pain after shingles.
- Nerve pain from spinal cord injury.
Benefits of Pregason-NT 75mg/10mg Tablet
The two ingredients attack nerve pain from separate angles, which may give better relief than either alone in people whose pain is hard to control. It can help reduce burning, tingling and shooting sensations associated with diabetic neuropathy, post-shingles pain and spinal cord injury, and may help with sleep disturbed by pain.
Side effects of Pregason-NT 75mg/10mg Tablet
Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.
- Dry mouth.
- Dizziness.
- Constipation.
- Nausea.
- Weight gain.
- Nasal congestion.
- Tremors.
- Headache.
How to use Pregason-NT 75mg/10mg Tablet
Swallow the tablet whole with water, usually once daily or as your doctor directs. Many doctors suggest taking it at bedtime because it can cause drowsiness. Keep to the prescribed dose and do not stop suddenly.
How Pregason-NT 75mg/10mg Tablet works
Pregabalin quiets overactive nerve cells by acting on calcium channels, lowering the release of pain-transmitting chemicals. Nortriptyline, a tricyclic antidepressant, raises levels of serotonin and noradrenaline in the brain and spinal pathways, which dampens the transmission of pain signals.
Substitutes for Pregason-NT 75mg/10mg Tablet
No other medicine with the same composition is listed in our catalogue yet. Message us on WhatsApp and our pharmacist will help you find a suitable alternative.
Safety advice
Alcohol can cause excessive drowsiness with this combination. Avoid it.
Safety in pregnancy has not been established. Discuss risks and benefits with your doctor.
The medicine may pass into breast milk and could affect the baby. Avoid unless your doctor advises.
It can cause dizziness, drowsiness and reduced alertness. Avoid driving.
Use with care in kidney disease. A dose adjustment may be required.
Use with care in liver disease. A dose adjustment may be required.
Quick tips
- Avoid alcohol, as it can greatly increase drowsiness.
- Do not drive or operate machinery until you know how the tablet affects you.
- Stand up slowly from sitting or lying to avoid dizziness.
- Sip water or chew sugar-free gum if you get a dry mouth.
- Tell your doctor about any other antidepressants or sedatives you take.
Fact box
| Chemical class | — |
|---|---|
| Habit forming | No |
| Therapeutic class | Neuro CNS |
| Action class | — |
Frequently asked questions
What is Pregason-NT used for?
It is prescribed for neuropathic pain arising from nerve damage due to conditions such as diabetes, shingles or spinal cord injury.
When is the best time to take it?
Your doctor will advise, but it is often taken at night because it can cause drowsiness.
Why does it cause a dry mouth?
Nortriptyline has drying effects on saliva glands. Sipping water frequently usually helps.
Can I take it with alcohol?
No. Alcohol can markedly increase sleepiness and dizziness.
Does it need a prescription?
Yes, it is a prescription-only medicine.