Product introduction
Nexpro RD 40 is a two-in-one capsule prescribed for acid reflux. It pairs esomeprazole, which cuts down the amount of acid the stomach produces, with domperidone, which helps the stomach and gut move food along more briskly. The domperidone part is in a sustained-release form, so its effect is spread out over time.
Storage: Store below 25°C, away from moisture and direct sunlight, and keep out of reach of children.
Uses of Nexpro RD 40 Capsule SR
- Gastroesophageal reflux disease (GERD) with acid reflux.
Benefits of Nexpro RD 40 Capsule SR
By lowering acid output and speeding up the emptying of the stomach, this combination helps reduce heartburn, a sour taste in the mouth, bloating and the feeling of food sitting heavily after a meal. It is useful when reflux is linked with slow stomach emptying, because both the acid and the sluggish movement are addressed together.
Side effects of Nexpro RD 40 Capsule SR
Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.
- Diarrhoea.
- Headache.
- Nausea.
- Abdominal pain.
- Sleepiness or dizziness in some people.
How to use Nexpro RD 40 Capsule SR
Swallow the capsule whole with water, without chewing, crushing or opening it. It is generally taken on an empty stomach, around 30 to 60 minutes before the first meal of the day, or exactly as your doctor has directed. Take it at about the same time each day and complete the course your doctor has advised.
How Nexpro RD 40 Capsule SR works
Esomeprazole is a proton pump inhibitor: it blocks the acid-producing pumps in the stomach lining, so less acid is made and the food pipe gets a chance to heal. Domperidone is a prokinetic: it increases the movement of the stomach and intestines so that food leaves the stomach faster and is less likely to wash back up.
Substitutes for Nexpro RD 40 Capsule SR
No other medicine with the same composition is listed in our catalogue yet. Message us on WhatsApp and our pharmacist will help you find a suitable alternative.
Safety advice
The effect of alcohol with this medicine is not well established, and alcohol can itself aggravate reflux. Check with your doctor before drinking.
There is some evidence of risk to the unborn baby, so this is not generally recommended. A doctor may still prescribe it if the benefit is judged to outweigh the risk.
The medicine may pass into breast milk and could be harmful to the baby, so it is best avoided while breastfeeding.
It can cause sleepiness, dizziness and reduced alertness in some people. Do not drive or use machinery if you feel any of these.
A dose adjustment may be needed in people with severe kidney disease. Your doctor will decide.
This medicine should be avoided in people with liver disease.
Quick tips
- Take this capsule on an empty stomach, ideally half an hour to an hour before your first meal.
- Swallow it whole and do not open, crush or chew the capsule.
- Cutting back on spicy and oily food, eating smaller meals and avoiding lying down right after eating will make the medicine work better.
- Tell your doctor if you develop persistent diarrhoea, fever or stomach pain while on this medicine.
- Long-term use can affect bone strength and mineral levels, so do not continue for months without medical review.
Fact box
| Chemical class | Proton pump inhibitor and prokinetic combination |
|---|---|
| Habit forming | No |
| Therapeutic class | Gastrointestinal |
| Action class | Proton pump inhibitor with prokinetic agent |
Frequently asked questions
When should I take Nexpro RD 40?
It is usually taken once a day on an empty stomach, 30 to 60 minutes before a meal, or as your doctor has prescribed.
Can I open the capsule and mix it with food?
No. The capsule is a sustained-release form and should be swallowed whole without being opened, chewed or crushed.
Is it safe to take for a long time?
Prolonged use of acid-reducing medicines can weaken bones and lower some minerals in the body, so it should only be continued as long as your doctor considers necessary.
Can I drive after taking it?
Avoid driving if the medicine makes you sleepy or dizzy, as it can reduce alertness.