Product introduction
Monotrate 10 Tablet contains isosorbide mononitrate, a nitrate medicine prescribed to prevent angina, the chest pain that occurs when the heart muscle does not get enough oxygen-rich blood. It is taken regularly to reduce how often attacks happen rather than to stop one that has already started.
Storage: Store below 30°C, away from moisture and out of reach of children.
Uses of Monotrate 10 Tablet
- Prevention of angina (heart-related chest pain).
Benefits of Monotrate 10 Tablet
Regular use can reduce the number and severity of angina episodes and make everyday activity more comfortable. By easing the workload on the heart, it helps improve exercise tolerance in people with coronary artery disease.
Side effects of Monotrate 10 Tablet
Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.
- Throbbing headache.
- Flushing.
- Upper respiratory tract infection.
- Abdominal discomfort.
- Allergic reactions.
- Chest pain.
- Diarrhoea.
How to use Monotrate 10 Tablet
Take the tablet exactly as your doctor has prescribed, usually with water at the same times each day. Swallow it whole and do not change the dose or timing on your own. It is a preventive medicine, so it should not be relied on to relieve a sudden angina attack.
How Monotrate 10 Tablet works
Isosorbide mononitrate releases nitric oxide in the body, which widens the veins and, to a lesser extent, the arteries. This lowers the amount of blood returning to the heart and reduces the heart's oxygen demand, so angina is less likely to occur.
Substitutes for Monotrate 10 Tablet
These medicines have the same composition (Isosorbide Mononitrate (10mg)) and can generally be used as alternatives. Always confirm with your doctor or our pharmacist before switching.
Safety advice
Alcohol can add to the blood-pressure lowering effect and cause dizziness, so limit it and check with your doctor.
Safety in pregnancy has not been firmly established. Your doctor will weigh the benefit against the possible risk.
It may pass into breast milk and may not be safe for the baby. Discuss with your doctor before using it.
It can cause dizziness and reduce alertness. Do not drive or operate machinery until you know how it affects you.
No dose adjustment is usually needed in kidney disease, but use it only as directed by your doctor.
No dose adjustment is usually needed in liver disease, but use it only as directed by your doctor.
Quick tips
- Never combine this medicine with sildenafil, tadalafil or vardenafil, as the combination can cause a dangerous fall in blood pressure.
- A mild headache is common at the start and often settles after a few days.
- Do not stop the tablet abruptly, as this can bring angina attacks back.
- Keep any fast-acting angina medicine your doctor has given you within reach.
- Rise slowly from sitting or lying down to avoid light-headedness.
Fact box
| Chemical class | Isosorbides |
|---|---|
| Habit forming | No |
| Therapeutic class | CARDIAC |
| Action class | Nitric Oxide (NO) Donors |
Frequently asked questions
Will Monotrate 10 stop an angina attack that has already started?
It is mainly used to prevent attacks. For sudden chest pain, use the fast-acting medicine your doctor has prescribed and seek urgent help if the pain does not ease.
Which medicines should I avoid with Monotrate 10?
Avoid erectile dysfunction medicines such as sildenafil, tadalafil and vardenafil, because together they can cause a severe drop in blood pressure. Always tell your doctor about every medicine you take.
Can I stop taking it when I feel better?
Do not stop suddenly. Stopping abruptly can increase the chance of angina returning, so ask your doctor before making any change.
Why do I get a headache after taking it?
The widening of blood vessels can cause a throbbing headache, especially early in treatment. It usually becomes milder with continued use; tell your doctor if it is troublesome.