Product introduction
Glynase-MF combines two diabetes medicines in a single tablet: glipizide and metformin. It is prescribed to adults whose type 2 diabetes is not controlled well enough with one medicine. Taking both in one tablet means fewer pills to remember.
Storage: Store below 30°C, in a dry place away from sunlight.
Uses of Glynase-MF Tablet
- Type 2 diabetes mellitus in adults.
Benefits of Glynase-MF Tablet
The two ingredients attack high blood sugar in different ways, so together they often control sugar better than either alone. One combined tablet can simplify a daily routine and may help people stick to their treatment. Better sugar control over time reduces the risk of complications affecting the eyes, kidneys and nerves.
Side effects of Glynase-MF Tablet
Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.
- Dizziness.
- Low blood sugar.
- Nausea.
- Diarrhoea.
- Abdominal pain.
- Muscle or joint pain.
- Upper respiratory tract infection.
- Urinary tract infection.
- Raised blood pressure.
- Vitamin B12 deficiency (with long-term use).
- Lactic acidosis (rare but serious).
How to use Glynase-MF Tablet
Take the tablet with food at the same time every day, exactly as your doctor has prescribed. Do not skip meals while on this medicine, as that can bring your sugar too low. Keep taking it even if your readings improve unless your doctor tells you to stop.
How Glynase-MF Tablet works
Glipizide prompts the pancreas to release more insulin, which lowers blood sugar. Metformin reduces the sugar made by the liver, slows its absorption from the gut and helps the body respond better to insulin. The two actions complement each other.
Substitutes for Glynase-MF Tablet
These medicines have the same composition (Glipizide (5mg) + Metformin (500mg)) and can generally be used as alternatives. Always confirm with your doctor or our pharmacist before switching.
Safety advice
Alcohol can cause dangerous drops in blood sugar and raises the risk of lactic acidosis with metformin. Avoid it.
Safety in pregnancy is not established. Your doctor will weigh the benefits against the risks and may switch you to insulin.
Use with caution. Your doctor may advise pausing breastfeeding or changing medicine.
Its effect on driving is not well defined. Low blood sugar can impair concentration, so avoid driving if you feel unwell or shaky.
The dose may need adjustment in kidney disease. Your doctor may monitor kidney function.
This combination should be avoided in people with liver disease.
Quick tips
- Take it with food and never skip meals.
- Keep glucose tablets or a sugary snack handy in case of low blood sugar.
- Monitor your blood sugar regularly as advised.
- Seek urgent help for deep or rapid breathing, severe tiredness or persistent vomiting, which can signal lactic acidosis.
- Avoid alcohol while taking this medicine.
Fact box
| Chemical class | Sulfonylurea + biguanide combination |
|---|---|
| Habit forming | No |
| Therapeutic class | Anti-diabetic |
| Action class | Oral antidiabetics |
Frequently asked questions
Why are two medicines combined in Glynase-MF?
Glipizide and metformin lower blood sugar through different routes. Combining them gives better control for people not managed by one drug alone.
What should I do if I feel shaky or sweaty?
These can be signs of low blood sugar. Have a glucose tablet or sugary drink right away and tell your doctor afterwards.
Can I stop it once my sugar is normal?
No. Normal readings usually mean the medicine is working. Stop only if your doctor says so.
Does long-term use affect vitamin levels?
Metformin can lower vitamin B12 over time. Your doctor may check your levels periodically.