Product introduction
Glyciphage SR 500 Tablet is a sustained-release form of Metformin, one of the most widely used medicines for type 2 diabetes. Being sustained-release, it dissolves slowly through the day, which usually means a simpler dosing schedule and gentler effect on the stomach compared with plain Metformin. Doctors also prescribe it off-label to manage insulin resistance in women with polycystic ovary syndrome. It works by tackling the root causes of high blood sugar rather than forcing extra insulin release.
Storage: Store below 30°C in a dry place away from direct sunlight.
Uses of Glyciphage SR 500 Tablet
- Management of type 2 diabetes mellitus
- Blood sugar control alongside diet and exercise
- Managing insulin resistance in polycystic ovary syndrome (PCOS)
Benefits of Glyciphage SR 500 Tablet
Lowers blood sugar without directly increasing insulin release, so the risk of severe hypoglycemia stays low,Sustained-release format can mean fewer stomach-related side effects than immediate-release Metformin,Helps reduce long-term diabetes complications affecting the kidneys, eyes, nerves, and limbs
Side effects of Glyciphage SR 500 Tablet
Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.
- Diarrhea
- Headache
- Vomiting
- Nausea
- Abdominal discomfort
- Flatulence
How to use Glyciphage SR 500 Tablet
Take once daily as prescribed, generally with or right after the evening meal,Swallow the tablet whole with a glass of water; do not crush, split, or chew it,Take it around the same time each day for steady blood sugar control
How Glyciphage SR 500 Tablet works
Reduces the amount of glucose the liver releases into the bloodstream,Slows down how much glucose the intestines absorb from digested food,Improves the sensitivity of muscle and fat cells to insulin so the body uses available glucose more efficiently
Substitutes for Glyciphage SR 500 Tablet
No other medicine with the same composition is listed in our catalogue yet. Message us on WhatsApp and our pharmacist will help you find a suitable alternative.
Safety advice
Alcohol should be avoided as it can increase the risk of lactic acidosis and low blood sugar when combined with Metformin.
Considered safe during pregnancy based on available studies showing low or no significant risk, though it should still be taken under medical supervision.
Limited studies suggest it may be used while breastfeeding when a doctor has advised it, with the infant monitored for any effects.
Does not usually impair alertness or reaction time, so it does not typically affect the ability to drive.
Should be used carefully in patients with significant kidney impairment, as reduced clearance raises safety concerns.
Generally considered acceptable for patients with liver disease under a doctor's guidance, though monitoring is still advised.
Quick tips
- Take it with food to minimise stomach upset
- Stay consistent with meals and physical activity for the best sugar control
- Avoid alcohol, which can add to the small risk of lactic acidosis
- Get kidney function checked periodically, especially with long-term use
- Do not stop taking it abruptly without talking to your doctor, even if sugar levels look normal
Fact box
| Chemical class | Biguanide derivative |
|---|---|
| Habit forming | No |
| Therapeutic class | Anti Diabetic |
| Action class | Biguanides |
Frequently asked questions
Can Glyciphage SR 500 Tablet be used for PCOS?
Yes, doctors often prescribe it to help manage insulin resistance that is common in polycystic ovary syndrome, alongside lifestyle changes.
Is this tablet suitable for someone with prediabetes?
It can be prescribed in early-stage or borderline blood sugar cases alongside diet and exercise, based on a doctor's assessment.
How is this different from medicines that boost insulin release?
Rather than pushing the pancreas to make more insulin, this tablet mainly improves how well the body's own insulin is used, which keeps the risk of severe hypoglycemia low.
How long does treatment usually continue?
Duration depends on individual blood sugar response and is decided by the treating doctor; many patients stay on it long-term as part of ongoing diabetes management.
Why is it taken with food?
Taking it with a meal helps reduce common stomach-related side effects like nausea and discomfort.