Product introduction
Depran L Tablet is a combination medicine containing escitalopram, an antidepressant, and clonazepam, a fast-acting anti-anxiety medicine. It is prescribed for generalised anxiety disorder, particularly when a person experiences both persistent worry and low mood together. The combination allows the escitalopram to work on mood over the longer term while clonazepam offers quicker relief from acute anxiety symptoms. Because it contains a benzodiazepine component, treatment duration and dose are strictly controlled by the prescribing doctor.
Storage: Store below 30°C, in a cool dry place away from direct sunlight
Uses of Depran L Tablet
- Generalised anxiety disorder
- Anxiety associated with low mood or depression
Benefits of Depran L Tablet
Addresses both the emotional low mood and the physical restlessness of combined anxiety and depression,Clonazepam component offers relatively faster relief from acute anxious symptoms while escitalopram builds a longer-term mood effect,Can improve sleep and concentration difficulties linked to ongoing anxiety
Side effects of Depran L Tablet
Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.
- Nausea
- Dry mouth
- Headache
- Dizziness
- Sleepiness
- Decreased appetite
How to use Depran L Tablet
Take Depran L exactly as prescribed, in the dose and for the duration your doctor sets.,Swallow the tablet whole with water; do not crush, chew, or break it.,It can be taken with or without food, ideally at the same time each day.
How Depran L Tablet works
Escitalopram is a selective serotonin reuptake inhibitor (SSRI) that raises serotonin levels in the brain, helping to lift mood over time.,Clonazepam enhances the activity of GABA, a calming brain chemical, which quickly reduces excessive anxiety and nervous tension.,Together, the two components address both the immediate anxiety symptoms and the underlying mood disturbance.
Substitutes for Depran L Tablet
These medicines have the same composition (Escitalopram Oxalate (10mg) + Clonazepam (0.5mg)) and can generally be used as alternatives. Always confirm with your doctor or our pharmacist before switching.
Safety advice
Alcohol should not be taken with Depran L, as it can cause dangerously deep drowsiness and slowed breathing.
This combination is considered unsafe in pregnancy and may cause serious harm to the unborn baby, so it should be avoided unless specifically directed by a doctor.
The medicine is considered unsafe during breastfeeding, as it may pass into breast milk and affect the infant.
Depran L can markedly reduce alertness and slow reflexes, so driving is not advisable while taking it.
Patients with significant kidney disease should use this medicine cautiously and may need dose adjustment.
This medicine is best avoided in patients with liver disease, as it is considered unsafe in this setting.
Quick tips
- Do not stop taking Depran L suddenly; your doctor will usually recommend tapering the dose gradually.
- Avoid alcohol entirely while on this medicine, as the combination can dangerously deepen sedation.
- It may take a few weeks for the antidepressant effect to become fully noticeable, even though the anti-anxiety effect can be faster.
- Do not drive or use machinery until you know how the tablet affects your alertness.
- Report any severe mood changes or thoughts of self-harm to your doctor right away.
Fact box
| Chemical class | Benzodiazepine and SSRI combination |
|---|---|
| Habit forming | Yes |
| Therapeutic class | Neuro (CNS) |
| Action class | Antidepressant and Anti-anxiety combination |
Frequently asked questions
Why does Depran L combine two different medicines?
It pairs escitalopram, which works gradually on mood, with clonazepam, which acts quickly on anxiety, so the combination addresses both the immediate and longer-term symptoms of anxiety with depression.
Is Depran L habit-forming?
Yes, because it contains clonazepam, a benzodiazepine, which can lead to dependence if used longer than prescribed. It should only be taken exactly as your doctor advises.
Can I stop Depran L once I feel better?
No, you should not stop on your own. Your doctor will typically taper the dose gradually to avoid withdrawal or rebound symptoms.
How soon will I feel the effect of Depran L?
The anti-anxiety effect from clonazepam may be felt sooner, but the mood-lifting effect from escitalopram usually takes a few weeks of regular use to become clear.
Can Depran L cause drowsiness?
Yes, drowsiness and dizziness are recognised effects, especially when starting treatment, so avoid driving or operating machinery until you know how it affects you.