Clonotril Plus 20/0.5 Tablet

Escitalopram Oxalate (20mg) + Clonazepam (0.5mg)

Marketed by Torrent Pharmaceuticals Ltd

Prescription requiredStrip of tablets
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Product introduction

Clonotril Plus pairs escitalopram, an SSRI antidepressant, with clonazepam, a benzodiazepine. It is a prescription-only medicine used for anxiety disorder and should be taken only under close medical supervision.

Storage: Store below 30°C, away from moisture and direct sunlight. Keep out of reach of children.

Uses of Clonotril Plus 20/0.5 Tablet

  • Anxiety disorders.

Benefits of Clonotril Plus 20/0.5 Tablet

The combination helps calm excessive worry and nervous tension while improving mood over time. Clonazepam can give quicker relief from anxiety symptoms while escitalopram builds its effect more gradually.

Side effects of Clonotril Plus 20/0.5 Tablet

Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.

  • Vomiting.
  • Nausea.
  • Diarrhoea.
  • Dry mouth.
  • Headache.
  • Dizziness.
  • Constipation.
  • Insomnia.
  • Sleepiness.
  • Decreased sex drive.
  • Ejaculation problems.

How to use Clonotril Plus 20/0.5 Tablet

Take the tablet exactly as your doctor has prescribed, swallowing it whole without chewing, crushing or breaking it. It may be taken with or without food, preferably at the same time each day to keep the level steady.

How Clonotril Plus 20/0.5 Tablet works

Clonazepam boosts the calming action of GABA, a brain chemical that quietens overactive nerve signals. Escitalopram raises serotonin levels in the brain, which helps lift mood and reduce anxiety. Together they ease anxiety symptoms through two different pathways.

Substitutes for Clonotril Plus 20/0.5 Tablet

No other medicine with the same composition is listed in our catalogue yet. Message us on WhatsApp and our pharmacist will help you find a suitable alternative.

Safety advice

AlcoholUNSAFE

Alcohol causes excessive drowsiness with this medicine and should be avoided.

PregnancyUNSAFE

May carry a risk of birth defects and pregnancy loss; avoid unless your doctor decides otherwise.

BreastfeedingUNSAFE

Not safe while breastfeeding as it may pass into milk and harm the infant.

DrivingUNSAFE

It causes drowsiness and reduces alertness, so do not drive or operate machinery.

KidneyCAUTION

The dose may need adjusting in severe kidney disease; consult your doctor.

LiverUNSAFE

Should be avoided in liver disease.

Quick tips

  • Take it only as prescribed; never increase the dose or extend the course by yourself.
  • Do not stop suddenly, as withdrawal symptoms and a return of anxiety can occur.
  • Avoid alcohol completely as it causes excessive drowsiness.
  • Be careful with driving or machinery until you know how the tablet affects you.
  • Tell your doctor at once if you notice worsening mood or thoughts of self-harm.

Fact box

Chemical classBenzodiazepine (clonazepam) combined with SSRI (escitalopram)
Habit formingYes
Therapeutic classNeuro CNS
Action classAntidepressants and mood stabilisers

Frequently asked questions

What is Clonotril Plus used for?

It is used to treat anxiety disorder and relieve symptoms such as excessive worry and tension.

Is Clonotril Plus habit forming?

Yes. It contains clonazepam, which can cause dependence, so use it only as prescribed and for the advised duration.

Can I drink alcohol with it?

No. Alcohol adds to the drowsiness and is unsafe with this medicine.

Can I stop it suddenly?

No. Stopping abruptly can cause withdrawal symptoms; your doctor will reduce the dose gradually.

Disclaimer: This information is for general awareness only and is not a substitute for professional medical advice. Always consult a doctor or our pharmacist before starting, stopping or changing any medicine. Medicines are dispensed only against a valid prescription where required.
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