Product introduction
Axinerve P Tablet SR is a combination medicine containing pregabalin and methylcobalamin, formulated as a sustained-release tablet for the management of nerve-related (neuropathic) pain. Pregabalin helps calm overactive nerve signals that cause pain, while methylcobalamin, a form of vitamin B12, supports the repair and health of nerve fibres. It is commonly prescribed for long-standing nerve pain linked to conditions such as diabetes, shingles, or spinal injury. This medicine is available only with a valid prescription and should be used under a doctor's supervision.
Storage: Store below 25°C
Uses of Axinerve P Tablet SR
- Treatment of neuropathic pain due to diabetes
- Nerve pain due to shingles (post-herpetic neuralgia)
- Nerve pain due to spinal cord injury
- Vitamin B12 support for nerve health
Benefits of Axinerve P Tablet SR
By combining a nerve-pain reliever with a vitamin that supports nerve health, this tablet aims to reduce pain intensity while also addressing an underlying vitamin B12 need that is common in people with nerve damage. The sustained-release formulation allows the medicine to act over an extended period, which can mean fewer doses through the day. Many patients find this combined approach more convenient than taking separate medicines for pain relief and nerve nourishment.
Side effects of Axinerve P Tablet SR
Most side effects do not require medical attention and go away as your body adjusts. Consult your doctor if they persist.
- Dizziness
- Sleepiness
- Headache
- Nausea
- Dry mouth
- Weight gain
How to use Axinerve P Tablet SR
Take Axinerve P Tablet SR by mouth as directed by your doctor, and swallow the tablet whole with water. Do not crush or chew the tablet, as this is a sustained-release formulation meant to release the medicine gradually over time. Try to take it at the same time each day, and continue the course for as long as your doctor recommends, even if the pain begins to improve.
How Axinerve P Tablet SR works
Pregabalin works by binding to calcium channels on overactive nerve cells, which reduces the release of certain pain-signalling chemicals and calms the abnormal nerve activity responsible for neuropathic pain. Methylcobalamin, an active form of vitamin B12, supports the production of myelin, the protective sheath around nerve fibres, and helps in the repair of nerve tissue. Together, the two ingredients target both the symptom of pain and the underlying nerve health.
Substitutes for Axinerve P Tablet SR
No other medicine with the same composition is listed in our catalogue yet. Message us on WhatsApp and our pharmacist will help you find a suitable alternative.
Safety advice
Alcohol should be avoided with this medicine as it can intensify drowsiness and dizziness.
Safety during pregnancy has not been well established, so this medicine should only be used if the doctor feels the benefits outweigh the possible risks.
Small amounts of the medicine may pass into breast milk, so it is generally best avoided while breastfeeding unless a doctor advises otherwise.
This medicine can cause dizziness, sleepiness, or blurred vision, so driving or operating machinery should be avoided until these effects are known.
People with reduced kidney function may need a lower dose, since pregabalin is cleared from the body mainly through the kidneys.
This medicine should be used carefully in people with liver disease, and the doctor may adjust the dose accordingly.
Quick tips
- Take the tablet at the same time daily to maintain steady pain relief.
- Avoid alcohol, as it can increase the drowsiness caused by this medicine.
- Do not drive or use heavy machinery until you know how the tablet affects your alertness.
- Rise slowly from sitting or lying down, since dizziness can occur, especially when starting treatment.
- Continue the medicine for the full duration advised by your doctor, even if the pain eases early.
Fact box
| Chemical class | GABA analogue (pregabalin) combined with Vitamin B12 (methylcobalamin) |
|---|---|
| Habit forming | No |
| Therapeutic class | Neuropathic pain management (Neuro CNS) |
| Action class | Calcium channel modulator (alpha-2-delta ligand) with neurotropic vitamin support |
Frequently asked questions
Why does this medicine contain both pregabalin and vitamin B12?
Pregabalin helps reduce nerve pain by calming overactive nerve signals, while methylcobalamin (vitamin B12) supports nerve repair and health. Combining them addresses both the pain and, in many cases, an associated vitamin B12 need seen in nerve damage.
How long does it take for Axinerve P Tablet SR to relieve nerve pain?
Pain relief can take anywhere from a few days to a few weeks of regular use, depending on the underlying cause and severity of nerve damage. It is important to continue taking the medicine as prescribed even if improvement feels gradual.
Can I stop taking this medicine as soon as my pain improves?
It is best not to stop the medicine abruptly without consulting your doctor, as sudden discontinuation of pregabalin-containing medicines can occasionally cause withdrawal-like symptoms. Your doctor may advise tapering the dose gradually.
Does Axinerve P Tablet SR cause drowsiness?
Yes, drowsiness, dizziness, and sleepiness are known effects of this medicine, particularly when starting treatment or after a dose increase. It is advisable to avoid driving or operating machinery until you know how it affects you.
Is this medicine habit-forming?
According to available prescribing information, this medicine is not classified as habit-forming, but it should still be used strictly as prescribed and not shared with others.